Scenario answers
Multi-AZ load balancer with one-AZ targets
Distribute healthy targets and sufficient surviving capacity across AZs. The load balancer alone does not make the application highly available.
Read replica versus Multi-AZ
Use Multi-AZ for managed in-Region availability. Use replicas primarily for read scaling and explicit promotion or DR.
Replication versus backup
Replication can copy unwanted writes and deletes. Keep protected backups and point-in-time recovery.
DNS failover
Move traffic only after data, capacity, application version, secrets, certificates, dependencies, and observability are ready.